VANGUARD PLUS

Vanguard Plus 5 L4 — 1 mL

Zoetis Vanguard Plus 5 L4 is a combination vaccine for dogs. It is not a medicine for treating an existing infection; it is used to stimulate immunity in healthy dogs. Drugs.com+1

What it protects against

It contains protection against:

• Canine distemper virus
• Canine adenovirus (associated with infectious canine hepatitis/respiratory disease)
• Canine parainfluenza
• Canine parvovirus
• Leptospira — four serovars: L. canicola, L. grippotyphosa, L. icterohaemorrhagiae, and L. pomona Drugs.com+1

So, in simple terms, Vanguard Plus 5 L4 = core puppy combination vaccine + L4 leptospirosis protection.

Dose: 1 mL

The standard labeled dose is 1 mL per dog, regardless of the dog's body weight. The freeze-dried vaccine is reconstituted with the supplied sterile diluent and then administered subcutaneously (SC) or intramuscularly (IM). Drugs.com+1

Typical puppy schedule

The product information specifies:

• 6 weeks or older: vaccination can begin.
• Under 9 weeks: generally 3 doses, 3 weeks apart.
• For dogs receiving the standard two-dose initial series: 2 doses, 3 weeks apart.
• Annual revaccination: one dose is recommended on the cited label. Drugs.com+1

The exact schedule can vary according to your veterinarian's vaccination protocol and the product registration in your country.

Important handling

This is a freeze-dried vaccine that must be reconstituted with its supplied diluent. It should be kept refrigerated; the cited product information specifies approximately 2–7°C and advises against improper storage. Drugs.com

Do not use it in a sick dog without veterinary assessment. Vaccines are intended primarily for healthy animals, and proper cold-chain storage is important.

If you tell me your dog's age and weight, and whether this is the first vaccination or a booster, I can explain exactly where Vanguard Plus 5 L4 1 mL fits into the vaccination schedule.